World Journal of
Pharmaceutical and Life Sciences

CONSTITUENTS AND ANTIMICROBIAL ACTIVITY OF HELIANTHUS ANNUUM (ASTERACEAE) OIL

Abdel Karim M.*, Osama N., Mai Mekki and Tohami Z.

ABSTRACT

Helianthus annuum is considered as a significant source of vegetable oil and vegetable protein. Seeds are rich in polyunsaturated and monounsaturated fatty acids. They also contain tocopherols, folates, vitamin B , copper and zinc.This plant contains some biologically interesting molecules including flavonoids, alkaloids, saponins and tannins.Seed oil and herb tincture are used traditionally as antitumor, antiasthmatic, antioxidant, antipyretic and antimicrobial. GC- MS analysis of Helianthus annuum oil revealed the presence of the following major components: i) 9-octadecenoic acid (Z)-, methyl ester (53.92 %) .ii) 9,12-octadecadienoic acid (Z,Z)-, methyl ester (32.70 %).iii) methyl stearate (6.15%). iv) hexadecanoic acid, methyl ester ( 5.23 %) .The oil was evaluated for its antimicrobial activity against five standard human pathogens. The oil showed moderate activity against Pseudomonas aeruginosa, Staphylococcus aureus and the fungal species Candida albicans.

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