World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

CONSTITUENTS AND ANTIMICROBIAL ACTIVITY OF SUDANESE ARISTOLOCHIA BRACTEOLATE LAM. (ARISTOLOCIACEAE) OIL

Abdel Karim M.*, Elham A., Alla M. and Mai Mekki

ABSTRACT

The objective of the present study is to investigate the constituents and antimicrobial activity of Aristolochia bracteolata oil. Twelve components were detected by GC-MS analysis. Major constituents are 9-octadecenoic acid methyl ester (52.96%), hexadecanoic acid methyl ester(28.36%) and methyl stearate(6.68%). The antimicrobial activity of the oil was evaluated by using disc diffusion bioassay against five standard human pathogens (Gram positive: Staphylococcus aureus and Bacillus subtitis; Gram negative: Escherichs coli and Pseudomonas aeruginosa and the fungal species Candida albicans). Aristolochia bracteolata oil showed moderate activity against Escherichs coli, Staphylococcus aureus and Candida albicans. However, the oil was inactive Pseudomonas aeruginosa and Bacillus subtilis.

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