World Journal of
Pharmaceutical and Life Sciences

EVALUATION OF PHENOLIC CONTENT, PHYSICO-CHEMICAL AND HPTLC ANALYSIS OF SOME HERBAL DRUGS USED IN SIDDHA SYSTEM FOR DIABETES

Anitha John*, V. L. Reena, M. Natarajan, B. Neethu Kannan, S. Ghanthi Kumar and A. Kanagarajan

ABSTRACT

Many herbs identified in Siddha system of medicine have potent anti-diabetic and anti-hyperglycemic activity for the management of diabetes. The phenolic compounds present in them act as antioxidants and show reduction in blood glucose levels. In the present study, Cassia auriculata Linn. (Flower), Coccinia indica Wight & Arn. (Whole plant), Gymnema sylvestre (Retz.) R. Br. ex Schult. (Leaf) and Tinospora cordifolia (Willd.) Miers ex Hook. F. & Thoms) (Whole plant) were selected to evaluate the phenolic content and also to fix the pharmacopoeial standards. The physico-chemical, preliminary phytochemical, HPTLC analyses and powder microscopy were carried out to ascertain the authenticity. All the results obtained helps in the identification of the selected plants and thereby ensures the quality of the plants from adulteration and substitution. The phenol content evaluated using UV spectrophotometer confirmed the presence of polyphenols in different concentrations which might be one of the reasons for the anti- diabetic activity of the selected plant materials.

[Full Text Article]   [Download Certificate]