World Journal of
Pharmaceutical and Life Sciences

ANTIBACTERIAL EVALUATION OF DIFFERENT EXTRACT OF PTERIS VITTATA AGAINST HUMAN PATHOGENS IN DOON VALLEY, UTTARAKHAND, INDIA

Maneesha Singh*, Div Kush, Chhaya Singh and Anju Rani

ABSTRACT

Pteris vittata L. has antimicrobial activity, antitumor activity, platelet aggregation, anti-inflammatory action, hypotensive, hypogycemic, antiviral and anti bacterial activity. Ethno medicinally, the whole plant is used for healing of wounds, for the relief of glandular swelling by the folklores of Orissa and also used for phytoextraction of heavy metals. The present study was carried out on the antibacterial activity of Pteris vittata in Doon valley, situated in foot hills of the Himalayas. Plant material was collected, dried and grinded out a powdered form which was then subjected to soxhlet extraction using different solvents in the increasing order of their polarity. Different extract of the plants revealed its antibacterial activity against the studied pathogenic bacterial strains. Out of the seven extracts assayed the ethyl acetate extract was most active against the studied bacterial strains. Therefore, minimum inhibitory concentration (MIC) of this extract was determined against the selected bacteria showing zones of inhibition ? 10mm.

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