World Journal of
Pharmaceutical and Life Sciences

AN OVERVIEW OF OCULAR DRUG DELIVERY

*Arnab Majumder, Dr. Falguni Patra and Dr. Beduin Mahanti

ABSTRACT

The major challenge featured by today’s apothecary and formulation man of science is ocular drug delivery. Topical eye drop is that the most convenient and patient compliant route of drug administration, particularly for the treatment of anterior section diseases. Also, therapeutic drug levels aren't maintained for extended length in target tissues. Within the past 20 years, ocular drug delivery analysis accelerated advanced towards developing a unique, safe and patient compliant formulation and drug delivery techniques, anterior phase drug delivery advances are witnessed by modulation of standard topical solutions with permeation and viscosity enhancers.The most commonly utilized conventional preparations of ophthalmic dosage forms are the solutions, suspensions and ointments which are relatively inefficient as therapeutic systems.By using prolonged drug delivery, the duration of drug action can be remarkably prolonged and also the frequency of drug administration can be reduced. Such a drug delivery can be achieved by designing formulations such as contact lens, microneedles, nanosuspension, nanoparticles, liposomes, dendrimers, nanomicelles which can act as efficient ocular drug delivery system.

[Full Text Article]   [Download Certificate]