World Journal of
Pharmaceutical and Life Sciences

STUDY OF INCREASED RISK FOR HYPERBILIRUBINEMIA IN TERM INFANTS DUE TO MATERNAL VITAMIN D DEFICIENCY

*Hussein Hamdan Mukhlif and Tahsin Abdulateef Hasan

ABSTRACT

The presence of hyperbilirubinemia frequently requires medical attention and hospital readmission. The aim of the present study was to determine the effect of maternal vitamin D deficiency on increased risk for hyperbilirubinemia in term newborns. This cross-sectional study was conducted on all pregnant women with gestational age of 38-42 weeks who were referred to Hadith general hospital, Al-Anbar province/Iraq from March to August 2019. Serum 25-hydroxyvitamin D was measured to 200 included pregnant women during birth time. The level of bilirubin was measured to their newborns at 3rd to 5th days of life. The level of 25-hydroxyvitamin D was low in 180 (90.0%) pregnant women. Hyperbilirubinemia was detected in 27(13.5%) newborns at the 3rd to 5th days of life. Maternal vitamin D during pregnancy showed a significant correlation with the levels of bilirubin in newborns (r= - 0.395, P<0.001). It can be concluded from this study that maternal vitamin D deficiency could be associated with the increased risk for neonatal hyperbilirubinemia.

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