World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

EVALUATION OF IN VITRO ANTI-UROLITHIATIC POTENTIAL OF MERREMIA TRIDENTATA (L.) HALLIER F. BY CALCIUM OXALATE DISSOLUTION ASSAY

Jisa Ann Sabu, *Dr. Brijithlal N.D. and Dr. Prakash G. Williams

ABSTRACT

Urolithiasis commonly known as stone formation is one of the most painful urological disorder. The present study was undertaken to evaluate the in vitro anti-urolithiatic activity of Merremia tridentata by calcium oxalate dissolution assay. The distilled water extract, ethanol extract, ethyl acetate extract, chloroform extract, lime juice extract and tender coconut water extract were taken for the evaluation. All the six extracts shown their effectiveness in the dissolution of calcium oxalate crystals. The ethyl acetate extract was more effective when compared to other extracts with a high rate of dissolution. The study revealed that Merremia tridentata possess potent anti-urolthiatic activity.

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