Abstract
A REVIEW ON MANAGEMENT OF SUBCLINICAL HYPOTHYROIDISM
G. Prasanth, P. Ramesh, G. Rajasekhar and V. Satyanarayana*
ABSTRACT
Subclinical hypothyroidism (SCH), also called mild thyroid failure, is diagnosed when thyroid hormone levels are within normal laboratory range but serum thyroid-stimulating hormone (TSH) levels are slightly elevated. This condition occurs in 3% to 8% of the general population. It is more seen in women than men, and its occurence increases with age. Of patients with SCH, 80% have a serum TSH of less than 10 mIU/. Subclinical hypothyroidism is high likelihood of progression to clinical hypothyroidism. Large-scale randomized studies are needed for evidence-based recommendations regarding screening for subclinical hypothyroidism and levothyroxine therapy for this condition. Currently, the practicable approach is routine levothyroxine therapy for persons with a persistent serum TSH of more than 10.0 mIU/L and individualized therapy for those with a TSH of less than 10.0 mIU/L.
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