World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

SYNTHESIS OF 2,3-DIPHENYL QUINOXALINE USING BIOCOMPATIBLE DEEP EUTECTIC SOLVENT.

Santosh Bansilal Katariya*

ABSTRACT

An efficient protocol for the synthesis of 2, 3-diphenyl quinoxaline in deep eutectic solvents under solvent-free conditions is reported here. Quinoxaline derivatives are well known in the pharmaceutical industry for their broad-spectrum of biological activities. The reaction is remarkably facile because of the air and water stability of the catalyst, and needs no special precautions. The reaction was completed within 25 minutes with excellent yield. The product formed was sufficiently pure, and can be easily recovered. The use of deep eutectic solvent choline chloride/urea in solid phase offered several significant advantages such as low cost, greater selectivity and easy isolation of products.

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