World Journal of
Pharmaceutical and Life Sciences

AN ASSESSMENT OF IN –VITRO ANTI-OXIDANT POTENTIAL OF SELECTED MEDICINAL PLANTS EXTRACTS

Prathiba H. D.* and Anupama Sindhghatta Kariyappa

ABSTRACT

The aim of the study was to evaluate the antioxidant activity of leaf extracts of five plant species selected on the basis of their reported ethno botanical uses. The alkaloid and flavonoid fraction of plant extracts was analyses against L-ascorobic acid by DDPH assay. The potential of L- ascorobic acid to scavenge DPPH (1,1-diphenyl-2-picrylhydrazyl) radical become almost stable after 70 or 80%. The fractions showed dose dependent free radical scavenging property. The alkaloids and flavonoids fraction of Abutilon indicum, leaf extract were found to 75.99% (ethanol), 79.16% (methanol), 75.04% (aqueous) and 77.02 %, 81.07%, 47.54%, respectively. The Adathoda visca leaf extracts were found to be 75.17%, 81.07%,71.32% and 79.16%, 85.10%, 44.32%, Datura stromonium 73.21%, 82.86%, 70.27% and 70.43%,75.46%, 41.17% respective Lantana camara fraction showed 70.22%, 80.92%, 70.50% and 68.47% 80.90%,37.72% activities and Tridax procumbens 72.07%,79.34%,68.80% and 62.27% 62.67%, 33.02%. On comparative basis flavonoids leaf extracts of Adathoda visca and Datura stromonium fractions exhibit amazing antioxidant properties that support their traditional use as natural antioxidant.

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