World Journal of
Pharmaceutical and Life Sciences

STANDARDISATION OF NOVEL SIDDHA FORMULATION SEENAKARA PARPAM

Dr. A. Mariappan*, Dr. S. Visweswaran, Dr. G. Kaaruniya, Dr. K. Ranjitham

ABSTRACT

Siddha system of medicine is a renowned holistic system of traditional medicine emphasizing curative and preventive measures. The medicines used in Siddha system are of plant origin, metals, minerals and animal products which is broadly classified into 32 types of internal and external medicines. Parpam is one among the type of internal medicines which is a nano sized formulation with a life expectancy of 100 years. Seenakara Parpam is a classical siddha formulation used in the treatment of Kalladaippu (Renal Calculi) and Neeradaippu (Obstruction of urethral passage). In present scientific scenario, standardisation of Siddha medicines has become mandatory to establish its safety, efficacy and to find out the active components present in it. The aim of this study is to standardise the nano formulation Seenakara Parpam (SKP) as per the siddha literature using sophisticated techniques like Elemental Analysis (AAS), Fourier Transform Infrared Spectroscopy (FTIR), X-Ray powder diffraction (XRD) and Scanning Electron Microscope (SEM). For more validity, three batches of SKP is prepared and analysed. On elemental analysis by AAS shows the presence of lead and mercury that too within the WHO prescribed limit. FTIR shows the presence of following functional groups viz.., C-H, N-H, O-H, C-N. SEM with EDAX proves presence of nano sized particles with minimum size of 42.1nm and highest of 184.7 nm.

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