World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

OVERVIEW ON OF SOLID DISPERSION TECHNOLOGY

Snehal S. Badadare*, Lokhande S. S. and Raje V. N.

ABSTRACT

Solid dispersion is one of the most promising strategies to improve oral bioavailability of poorly soluble API. Solid dispersions have attracted considerable interest as an efficient means of improving the dissolution rate and hence the bioavailability of a range of poorly water-soluble drugs. Solid dispersions of poorly water-soluble drugs with water-soluble carriers have been reduced the incidence of these problems and enhanced dissolution. This review article mainly focuses on solubility ranges, biopharmaceutical classification system (BCS), list of poorly soluble drugs, commercial preparations, classification, types, and advantages, and limitations, methods of preparation and characterization of solid dispersions.

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