World Journal of
Pharmaceutical and Life Sciences

A CLINICAL STUDY ON THE MANAGEMENT OF VITAMIN B12 (COBALAMIN) DEFICIENCY POLYNEUROPATHY WITH AMALAKI RASAYANA

*Dr. Jivesh Kumar Mehta and Dr. Shailesh V. Deshpande

ABSTRACT

Vitamin B12 is an essential vitamin that has a important role in the functioning of peripheral and central nervous system. Adequate B12 status is crucial for normal neuro-development as its deficiency affects the nervous system, resulting in demyelination of peripheral and central neurons, which is generally considered to be the mechanism underlying the classic neuropathy of B12 deficiency. The reasonable way to understand cobalamin deficiency polyneuropathy comes around a subcategory of Vata vyadhi. Rasayana due to its antioxidant & adaptogenic qualities is an excellent remedy to correct these abnormalities. Materials and Methods: Twenty cases of Vitamin B12 deficiency polyneuropathy were diagnosed. Ten cases were administered with Amalaki Rasayana & ten cases were administered with Methycobalamin. The outcome was assessed on ACTG peripheral neuropathy symptom score. Results: Amalaki rasayana shows significant improvement in pain, location of pain , numbness, location of numbness, symptoms grading score & serum B12 values. Discussion: The action of the drug is due to the acting properties of the drug viz, Rasayana as well as Vatahara & Srotoshodhana and giving significant improvements in subjective and objective parameters of assessment. Conclusion: The study confirms that Amalaki rasayana selected for the study is effective in treating the disease.

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