World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

FORMULATION AND CHARACTERIZATION OF SUSTAINED RELEASE BUCCOADHESIVE TABLETS OF LANSOPRAZOLE.

*P. Anvesh, Dr. Anna Balaji, M. Karthik and J. Bharath Kumar

ABSTRACT

The aim of this study was to formulate and investigate the in vitro performance of Lansoprazole .Lansoprazole can certainly be administered through the oral mucosa. The designed buccoadhesive tablets can overcome the disadvantage of extensive first pass effect and side effects of Lansoprazole. Lansoprazole, an acid proton-pump inhibitor similar to omeprazole, is used as an untiulcer drug in the treatment and maintenance of healing of duodenal or gastric ulcers, erosive and reflux esophagitis, NSAID-induced ulcer, Zollinger-Ellison syndrome, and Barrett's esophagus. Lansoprozole is active against Helicobacter pylori. Lansoprazole buccoadhesive tablets was formulate with following materials like Carboxy methyl cellulose, Carbopol 934P, Mannitol, Micro crystalline cellulose, Aspartame show better bioavailability.

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