World Journal of
Pharmaceutical and Life Sciences

CLINICAL EVALUATION OF EFFICACY OF VATANKURADI LEPA IN THE MANAGEMENT OF VYANGA W.S.R. TO MELASMA

Pratibha Mapari*, Amol Thote and Dr. Manu R.

ABSTRACT

The Beauty and Attraction of individual is reflected in the skins health. Skin diseases though afflicts bodily but gives lot of Psychological disturbances. Vyanga is one among Kshudra Rogas, in the disease Vyanga an important sign is the presence of Neeruja, Tanu, Shyavavarnayukta Mandala on Mukhapradesha. The disease Vyanga can be correlated with Hyper Pigmentation of skin due to over production of Melanin pigment occur in disease Melasma and the Patches of Hyper Pigmentation are seen especially on cheeks, nose, forehead and chin. Materials and Methods: 1. Measuring tape. 2. Graph Paper. 3. MSS[Melasma Severity Scale]. 4. Modified MASI Score. Objective: To evaluate the efficacy of Vatankuradi Lepa in the management of Vyanga. Study Design: open labelled clinical study. Study selection: Diagnosed cases of Vyanga, were selected from Opd and Ipd of Kayachikitsa and Stree-prasuti Department of Parul Ayurved Hospital, Parul University and referred cases from other Departments. Intervention: Selected patients were treated with “Vatankuradi Lepa” Dose 5 gm Powdered drug +10-15 ml luke warm water or milk, for 1 month. Main outcome measures: Based on the assessment criteria’s the parameters are graded and statistically analysed using Paired ‘t’ test. Results: In this study, the subjective and objective parameter shows significant values, The objective parameter like colour & size of lesion shows significant value and there is no any change was found in case of number of lesion and no any reduction was found in number of lesions, they remain same. The Kandu and Daha was absent before and after treatment, Rookshata found before treatment was reduced after treatment Snigdhata was increases up to some extent. Conclusion: So the results obtained from the Statistical observation Shows that Vatankuradi Lepa has been effective in Reducing the Size and Colour of skin lesion[Vyanga]. The Number of Skin Lesions were Statistically not Significant and the effect of Medication on Modified MASI Score is Statistically Significant, thus proving its efficacy.

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