World Journal of
Pharmaceutical and Life Sciences

PHYTOCHEMICAL SCREENING AND EVALUATION OF ANTIBACTERIAL AND ANTIOXIDANT ACTIVITY OF DIFFERENT EXTRACTS FROM CLERODENDRUM VISCOSUM

Tanushree Pal, Kamrun Nahar, Jerin Alauddin, Tahmina Khondkar Mitu, Tonima Enam and Sharif Md. Al-Reza*

ABSTRACT

The present study deals with the preliminary phytochemical screening and determination of antibacterial and antioxidant activity of various extracts from different parts of clerodendrum viscosum. The results revealed the presence of phenolic compounds, flavonoids, terpenoids, alkaloids, saponins, tannins and steroids in the extracts. All the extracts exhibited antibacterial effect against the tested bacteria with the diameter of inhibition zone ranging from 9.0 to 13 mm, however, highest antibacterial activity was observed by methanol extracts. In some cases, the organic extracts exhibited almost similar activity compared with standard sample streptomycin. The antioxidant potential of the samples was evaluated using 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. Among the extracts, the strongest activity was exhibited by the ethyl acetate extract of steam with an IC50 value of 12.29±0.9 ?g/ml. The preliminary studies on clerodendrum viscosum extracts exhibited their antibacterial and antioxidant potential which could be exploited further as future antimicrobials for pharmaceutical treatment, natural therapies, food preservation and cosmetic applications.

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