World Journal of
Pharmaceutical and Life Sciences

AN EFFECT OF ANTIMICROBIAL POTENTIALS OF A NOVEL SIDDHA METALLO-MINERAL FORMULATION “KAALAMEGA NARAYANA CHENDHOORAM” AS MENTIONED IN “ATHMARAKSHA MIRTHAM ENNUM VAITHIYA SAARA SANGERAHAM” AGAINST A GRAM NEGATIVE ORGANISMS KLEBSIELLA PNEUMONIA, PSEUDOMONAS

Dr. R. Abinaya*, Dr. R. Vijaya Nirmala, Dr. R. Karolin Daisy Rani, Dr. M. D. Saravana Devi

ABSTRACT

Aim And Objective: The aim of the present study is to validate the Anti microbial potentials of a novel siddha metallo-mineral formulation Kaalamega Narayana Chendhooram as mentioned in Athmaraksha Mirtham Ennum Vaithiya Saara Sangeraham against a Gram negative organisms such as Klebsiella Pneumonia, Pseudomonas Aeroginosa in in-vitro Studies. Methods: Siddha system of medicine is one of the traditional system of medicine plays an important role in treating various acute and chronic ailments without any adverse effect. The super natural scientists gave a boon of siddha system of medicine which have the solutions for various diseases including microbial infections. There is a huge need for antimicrobials due to the resistance of micro-oraganism. Thus an attempt was made to screen the anti microbial potentials of Kaalamega Narayana Chendhooram as mentioned in Athmaraksha Mirtham Ennum Vaithiya Saara Sangeraham, a novel siddha metallo-mineral formulation against a Gram negative organisms Klebsiella Pneumonia, Pseudomonas Aeroginosa in In-vitro Studies of Muller Hinton Agar Medium with streptomycin as a standard drug and test drug with the different concentration of the drug as 250?g/ml, 500?g/ml, 1000 ?g/ml were added and zone of inhibitions were measured in mm. Results: At the end of this research study, that the trail drug of a novel siddha metallo-mineral formulation Kaalamega Narayana Chendhooram as mentioned in Athmaraksha Mirtham Ennum Vaithiya Saara Sangeraham through Muller Hinton Agar Medium with streptomycin as standard drug. The gram negative organisms shows the zone of inhibition in following concentration Klebsiella Pneumonia 250?g/ml, 500?g/ml, 1000 ?g/ml as 17mm,19mm, 23mm , Pseudomonas Aeroginosa 250?g/ml, 500?g/ml, 1000 ?g/ml as 19mm, 20mm, 23mm. On increasing the concentration of the drug there is a gradual increase zone of inhibition of micro organisms. Conclusion: The present in-vitro study of a potent siddha metallo-mineral formulation Kaalamega Narayana Chendhooram as mentioned in Athmaraksha Mirtham Ennum Vaithiya Saara Sangeraham through a Muller Hinton Agar Medium with streptomycin as a standard drug was found to be a potent anti-microbial medicine.

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