World Journal of
Pharmaceutical and Life Sciences

HAIR GROWTH ACTIVITY AND ANTIOXIDANT ACTIVITY OF ANGIOPTERIS EVECTA (A EVECTA)

Khin Phyu Phyu, Myo Nanda Aung*, Maung Maung Mya, Aye Win Oo, Mu Mu Sein Myint, Khine Khine Lwin, Phyo Wai Zin

ABSTRACT

One of the problems often experienced by humans is baldness or hair growth that is not normal. Angiopteris evecta is one of the traditional indigenous medicinal plants which have many pharmacological properties. Hair growth activity of A evecta was determined in adult rabbit. Skin irritation test of rabbit was carried out by using ethanol and watery extracts of A evecta. Irritation degree was negligible. Mean length of hair growth for negative control was 0.74 cm and that of standard minoxidil was 1.5 cm. For watery extract, mean length of hair growth of 10 %, 20 % and 40 % were 0.82 cm, 1.28 cm and 1.4 cm, respectively. For ethanolic extract, mean length of hair growth of 10 %, 20 % and 40 % were 0.81 cm, 1.29 cm and 1.39 cm, respectively. The rabbit treated with ethanolic and watery extracts of A evecta showed increased in hair length when compared with those of control group (p<0.01). Therefore, it can be concluded that ethanolic and watery extracts of A evecta had increased in hair growth activity. In antioxidant activity, IC 50 values of watery extract of A evecta was 1.5595mg/ml and IC 50 values of ascorbic acid was 1.1040 mg/ml. A evecta rhizome contained high amount of Zn (51.32±0.01 ppm) and Fe (25.28±0.02 ppm) which were above the permissible limits set by WHO, 2008 in edible plants (Fe=20 ppm and Zn=27.4 ppm) and the absence of toxic contaminants (Cd, Cr, As and Pb) in their rhizomes of A evecta.

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