World Journal of
Pharmaceutical and Life Sciences

IS OSTEOPOROSIS COMMONN IN PEPTIC ULCER DISEASE?

*Dr. Shazia Naureen, Yamna Saeed and Amna Minhas

ABSTRACT

Objective: Frequency of osteoporosis in cases presenting with peptic ulcer disease. Study setting; Cross-sectional Setting; Department of Medicine, Sir Ganga Ram Hospital and National Hospital and Medical centre, Lahore Duration; February 2018 to September 2018. Methodology; The cases presenting with history of epigastric pain with age > 20 years of both gender was considered. These cases then underwent upper GI endoscopy and finally the 100 cases of peptic ulcer were considered. The detailed data was collected. The cases with previous history of bone trauma, metabolic disorders, end stage renal or liver disease and those with diabetes mellitus were excluded. The cases with diagnosed PUD then underwent DEXA scan and score less than 2.5 was labeled with osteoporosis. Results; In this study there were total 150 cases of PUD with mean age of 37.13±7.69 years. There were 66 (%) males and 84 (%) females. Mean duration of PUD was 1.9±0.5 years. Osteoporosis was seen in 14 (9.33%) out of 150 cases. There was no significant difference in terms of gender and age with p values of 0.95 and 0.87 respectively; though it was more common in females and age 40 years or more. It was also more seen in cases with duration of PUD > 1 year affecting 10 (11.11%) cases with p value of 0.08. Conclusion: Osteoporosis is not that common in peptic ulcer disease and is more seen in cases with PUD > 1 year.

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