World Journal of
Pharmaceutical and Life Sciences

ANTI-INFLAMMATORY ACTIVITY OF ETHANOLIC EXTRACT OF LEAVES BRYOPHYLLUM PINNATUM LINN

Dr. N. Naidu*, K. Chinna Venkata Rao, A. Asha Shaini, B. Kavitha, B. Sowjanya, D. Mahendra, Ch.M.M.Prasada Rao

ABSTRACT

The present study is carried out to investigate the anti-inflammatory potential of Ethanolic extract of Bryophyllum pinnatum. Anti-inflammatory activity was evaluated by using Egg Albumin, Turpentine Oil & Formaldehyde as phlogistic agents. The animals were treated with doses 250mg/kg and 500mg/kg of extract and Diclofenac Sodium at a dose of 10mg/kg is used as a standard drug. The Bryophyllum Pinnatum showed a significant antiinflammatory activity in a dose dependent manner in all the models when compared with the standard treatment. The extract (500mg/kg) exhibited maximum antiinflammatory activity i.e., 46.25%, 44.30%, 46.40% (P<0.001) like standard Diclofenac 47.02%, 46.50%, 48.57% in Egg albumin, Turpentine oil and Formaldehyde induced methods respectively. Based on the above results, we conclude that the Bryophyllum pinnatumhas significant antiinflammatory activity and might prove efficacious for further design and development of agents with significant biological activity.

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