World Journal of
Pharmaceutical and Life Sciences

EFFECT OF CADMIUM CHLORIDE (CdCl2) ON THE GALL BLADDER OF CLARIAS BATRACHUS (LINN. 1758)

Beena Joshi Bhatt* and Nighat Gull

ABSTRACT

Cadmium has various adverse effects on aquatic fauna. Fish play an integral role in the aquatic ecosystem food web and any effects that change the population structure of fish may also alter community and food web dynamics. The consumption of fish is recommended because it is a good source of omega - 3 - fatty acids, which have been associated with health benefits due to cardio - protective effect. However the content of heavy metals such as cadmium discovered in some fishes makes it difficult to establish clearly the role of fish consumption on a healthy diet. In the present investigation Clarias batrachus were exposed to chronic treatment up to30 days Cadmium chloride (0.05ppm, 0.5ppm,1ppm) The treated Clarias batrachus showed anomaly in normal histology of gall bladder. Fish at 1ppm concentration showed motility after 28 days. The 0.05ppm conc. shows the deformities in the normal structures of epithelial line, muscular layer, and mucosal folds. Columnar epithelial cells get destroyed at many places due to cadmium intoxication. In the same way mucosal folds also destroyed and deformities in the muscular layer appear due to destruction of smooth muscle cells. The changes after treatment with 0.5 ppm concentration of cadmium chloride are evidence for crystallization of bile in the lumen of the gall bladder. This may be due to excess loss of water. It also shows rupturing of submucosa. While mortality was recorded in 1 ppm concentration after 28 days. Control fish slides show normal histology.

[Full Text Article]   [Download Certificate]