World Journal of
Pharmaceutical and Life Sciences

GATRO-OESOPHAGEAL VARICES IN LIVER CIRRHOSIS

Sundas Saeed, Ayesha Pervaiz and Muhammad Ahmad*

ABSTRACT

Objective: To determine the frequency of gastro-esophageal varices in cases with cirrhotic liver. Methods: This study was carried out at Emergency department of Sir Ganga Ram Hospital, Lahore during July to December 2017. In this cross-sectionals study, 100 cases of cirrhotic liver were included of both gender and age more than 30 years. Cirrhotic liver was labeled as yes when there was reduced liver size less than 10 cm and with or without portal vein dilatation of more than 1 cm and with parenchymal changes. After collection of laboratory and clinical data these cases underwent upper GI endoscopy to look for the presence of varices of any grade. Results: In this study 100 cirrhotic cases were included comprising 57% males ad 43% females with mean age of 51.33±5.78 years. There were 57% cases I child pugh class B. GOV were seen in 30 (30%) of the cases. GOV were significantly high in cases that had liver cirrhosis for more than 3 years and was seen in 26 (38.23%) of cases with p= 0.01. GOV were also significantly high in class B and C with p= 0.03. Conclusion: GOV varices are seen in every 3rd cases of cirrhosis and significantly high in Child pugh class B & C and with cirrhosis duration more than 3 years.

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