World Journal of
Pharmaceutical and Life Sciences

PARAPHENYLENE POISONING AND ITS COMPLICATIONS

Bakhtawar Jabeen*, Sumera Zia and Salman Sarwar

ABSTRACT

Objective; To determine the various complications associated with Paraphenylene poisoning. Methods; In this study 50 cases of Paraphenylene poisoning were included on non-probability consecutive sampling. The cases were selected irrespective of gender and age group. The study was done at Department of Medicine Sheikh Zayed Hospital, Rahim Yar Khan during January to June 2018. These cases were followed for 48 hours and extensive clinical examinations, investigations and ECG done to look for various complications associated with it. Results; Out of the 50 cases in the present study, there were 33 (66%) females and 17 (34%) males. The mean age of the cases was 27.34±4.57 years and mean duration of poisoning was 5.67±1.03 hours. Complications were seen in 44 (88%) of the cases with overlapping of complications in most of the cases having one or more of it. The most common one was dysphagia seen in 38 (76%) of cases followed by hyperkalemia in 28 (56%) and maxillofacial edema in 22 (44%) of the cases. Renal failure and arrhythmias were seen in 28% and 32% of cases. Conclusion; Paraphenylene is a highly morbid condition and the most common one is dysphagia.

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