World Journal of
Pharmaceutical and Life Sciences

SPONTANEOUS BACTERIAL PERITONITIS (SBP) IN CASES WITH LIVER CIRRHOSIS

Dr. Mahpara Raza*, Kinza Bhatti and Aroosh Khan

ABSTRACT

Objective: Frequency of SBP in cases presenting with liver cirrhosis. Methodology: This Cross sectional study was done at Medical Department of Holy Family Hospital, Rawalpindi during July 2017 to December 2017. The cases of liver cirrhosis of at least one year irrespective of the age and gender suffering from hepatitis B and C were selected. SBP was labeled on the basis of fever, abdominal pain and supported by the laboratory data of serum ascitic albumin gradient >1.1, TLC more than 500/ml and Neutrophil count more than 250/ml. Results: In this study 100 liver cirrhotic cases were selected. Out of these 71% were males and the mean age of the cases of this study was 55.24±7.13 years of. There were 62% of the cases in Child pugh class B. SBP was seen in 24 (24%) out of 100 cases. SBP was more common in cases with child Pugh class C where this was observed in 16 (42.10%) of cases with p= 0.02. SBP was also significantly high in cases that had duration of cirrhosis for more than 5 years affecting 19 (33.33%) of cases with p= 0.03. Conclusion: SBP is a fatal complication of liver cirrhosis and is significantly associated with duration of cirrhosis and child pugh class C.

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