World Journal of
Pharmaceutical and Life Sciences

HYDROCEPHALUS AND TUBERCULOUS MENINGITIS

*Nayab Mustansar, Sana Naveed and Suman Javaid

ABSTRACT

Objectives: Frequency of hydrocephalus development in cases suffering from Tuberculosis meningitis (TBM). Material and methodology; In this cross sectional study carried out at Lahore General Hospital, Lahore during November 2017 to May 2018, the cases of both genders and adult range of age i.e. more than 12 years were selected. The diagnosis of TBM was made on the basis of fever, drowsiness, nuchal rigidity and characteristic exudative lymphocytic picture on CSF analysis. The diagnosis of hydrocephalus was made on the basis of CT brain without contrast showing dilated ventricles of more than 50% of the normal for that age. Results; In the present study, 100 cases of TBM were selected with mean age of 34.57±9.23 years. There were 62 (62%) males and 58 (58%) had stage II of BMRC scale of TBM. Hydrocephalus was seen in 56 (56%) of the cases. Hydrocephalus was seen more in females affecting 24 (63.15%) of the cases with p= 0.34. Hydrocephalus was significantly high in stage III affecting 29 (70.73%) cases as compared to 27 (47.36%) cases in stage II and none of the cases in grade I in their subgroups with p= 0.01. Conclusion; Hydrocephalus is seen in almost half of the cases suffering from TBM and it is significantly high in stage III of TBM.

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