World Journal of
Pharmaceutical and Life Sciences

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
World Journal of Pharmaceutical and Life Sciences (WJPLS) has indexed with various reputed international bodies like : Google Scholar, Index Copernicus, Indian Science Publications, SOCOLAR, China, Cosmos Impact Factor, Research Bible, Fuchu, Tokyo. JAPAN, Scientific Indexing Services (SIS), Jour Informatics (Under Process), UDLedge Science Citation Index, Global Impact Factor (In Process), International Impact Factor Services, International Scientific Indexing, UAE, International Society for Research Activity (ISRA) Journal Impact Factor (JIF), Science Library Index, Dubai, United Arab Emirates, International Innovative Journal Impact Factor (IIJIF), Scientific Journal Impact Factor (SJIF), Eurasian Scientific Journal Index (ESJI), Indian citation Index (ICI), IFSIJ Measure of Journal Quality, 

Abstract

ASSESMENT OF MICROBIAL QUALITY OF SOME PHARMACEUTICAL SYRUPS AVAILABLE IN UYO LGA OF AKWA IBOM STATE

Akeem Agboke* and Nneoma Igbokwe

ABSTRACT

This study was designed to evaluate the microbial quality of some pharmaceutical syrups available in Uyo LGA, Akwa Ibom. The microbiological quality of 10 different syrup samples of 10 pharmaceutical companies was assessed. The total aerobic microbial count (TAMC) varied between 1.0×103 CFU/ml and 6.0×103 CFU/ml.The total yeast and mold count (TYMC) ranged from 1.0×103 CFU/ml to 2×103 CFU/ml. In general, the microbiological qualities of six (6) which is 60% of the syrups tested have viable bacterial load within USP acceptable limits while four (4) which is 40% fell above stipulated standards. None of the syrups tested contained objectionable microbe (E.coli). Three samples of the syrups did not contain any mould while five samples of the syrups contained moulds which were within acceptable limits of USP. Two samples of the syrups contained moulds well above the stipulated standard. This work showed that quality of syrups that conformed to the standards was well prepared according to Current Good Manufacturing Practice (CGMP), while some might be contaminated during distribution and storage.

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