World Journal of
Pharmaceutical and Life Sciences

EFFECT OF SEASONALITY ON ANTIBACTERIAL AND ANTIOXIDANT ACTIVITY OF ERYTHROXYLUM ARGENTINUM O. E. SCHULZ AND ERYTHROXYLUM DECIDUUM ST. HIL

Arno Ernesto Hofmann Junior*, Janaina Tomazin, Bruna Maria Saorin Puton, Rogério Luís Cansian, Jean Carlos Budke, Neiva Aparecida Grazziotin and Renata Perreira Limberger*

ABSTRACT

The genus Erythroxylum presents about 240 species in pantropical distribution and the Brazil is the diversity center, with 114 species. The antimicrobial and antioxidant activities were identified for several species of the genus. In the Rio Grande do Sul and Santa Catarina states, South of Brazil, occur mainly E. argentinum e E. deciduum, in both the presence of some metabolites and the toxicity presented variation with the seasonality. Thus, the influence of climatic stations, summer and winter, about the antimicrobial and antioxidant activities was investigated for different extracts of this species. The study demonstrates wich the activities are influenced by climatic stations, the ethanolic extracts are more actives for the activities investigated and E. argentinum, summer collection, presents potential for the discovery of antimicrobial agents against Staphylococcus aureus.

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