World Journal of
Pharmaceutical and Life Sciences

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

ANTIFUNGAL AND PHYTOCHEMICAL CONSTITUENTS STUDY OF CLOVE OIL FROM SYZYGIUM AROMATICUM

Fateh A. L. Rahman F. Magbool, Elamin Ibrahim Elnima, Shayoub M. E., *Dr. Salah Eldin Omar Hussein

ABSTRACT

Introduction: Phytochemical screening and antimicrobial sensitivity of clove flower (Syzygium aromaticum) was studied. Materials and methods: Clove oil from Syzygium aromaticum showed strong activity against all the tested fungal isolates at various concentrations of 100mg/ml, 50mg/ml, 25mg/ml, 12.5mg/ml and 6.25mg/ml. The tested fungal isolates were Aspergillus niger and Candida albicans. Results: All the isolates were sensitive to the aqueous extract of Cloves flower (S. aromaticum). The highest sensitivity of 27 mm was observed in Aspergillus niger at 100mg/ml while at concentration of 12.5 mg/ml showed the same sensitivity against both Aspergillus niger and Candida albicans. The Minimum Fungicidal Concentration (MFC) of 6.25 mg/ml was observed for all fungi isolates used. Various phytochemicals tested were present in S. aromaticum these include flavonoids, tannins, saponins, anthraquinones and triterpenes. The results of this study showed that the extract of S. aromaticum has potent bioactivity against all fungi isolates studed. The presence of phytochemical in the extracts may have been responsible for the antifungal activity exhibited by the plant extract.

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