World Journal of
Pharmaceutical and Life Sciences

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

DETERIMNATION OF AFLATOXINS IN GROUNDNUT (ARACHIS HYPOGEA) SOLD IN NNEWI MARKET, NNEWI NORTH L.G.A OF ANAMBRA STATE

Obi M. C., Ochiabuto O. M .T. B., Chukwuma L. N., Onwuasoanya U. F., Ekwunoh P. O., Unaeze B. C. and Obeagu E. I.*

ABSTRACT

Aflatoxins are potent toxic, carcinogenic, mutagenic immunosuppressive agent produced as secondary metabolites by some fungi causing aflatoxicosis in humans and animals.A total of 20kg of raw and boiled bold type of groundnuts (Arachins hypoges)each were randomly collected in the dry and rainy seasons from 10 different locations at Nkwo Nnewi Market Nnewi North L. G. A, Anambra state. 25 gms of groundnuts from each location were extracted and analyzed using AOAC analytic method (Association of official analytical chemists).The results showed that aflatoxins were detected in both raw and boiled samples using high performance liquid chromatography (HPLC). The percentage positive for aflatoxin in boiled and raw samples in rainy season was 42% and 41% respectively while in dry season, the percentage positive for boiled and raw samples were 49% and 45% respectively. In dry season, the total mean value for boiled groundnut was 4.200 + 0.362 while the raw groundnut had a total mean value of 4.110 + 0.530. In rainy season, the total mean value for boiled groundnut was 4.940 + 0.480 while the raw groundnut had a total mean value of 4.590 +0.545. The total content of aflatoxin was 83nglml and an average daily intake 4.15nglml during rainy season while the total content of aflatoxin during dry season was 95nglml and an average daily intake of 4.75nglml.From the result, it showed that there is a risk in consumption if taken daily, since the acceptable range for European union and food and drug agency (FAO) is from 4-20nglml.

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