World Journal of
Pharmaceutical and Life Sciences

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
World Journal of Pharmaceutical and Life Sciences (WJPLS) has indexed with various reputed international bodies like : Google Scholar, Index Copernicus, Indian Science Publications, SOCOLAR, China, Cosmos Impact Factor, Research Bible, Fuchu, Tokyo. JAPAN, Scientific Indexing Services (SIS), Jour Informatics (Under Process), UDLedge Science Citation Index, Global Impact Factor (In Process), International Impact Factor Services, International Scientific Indexing, UAE, International Society for Research Activity (ISRA) Journal Impact Factor (JIF), Science Library Index, Dubai, United Arab Emirates, International Innovative Journal Impact Factor (IIJIF), Scientific Journal Impact Factor (SJIF), Eurasian Scientific Journal Index (ESJI), Indian citation Index (ICI), IFSIJ Measure of Journal Quality, International Scientific Indexing, UAE (ISI), 

Abstract

GC-MS ANALYSIS AND ANTIMICROBIAL ACTIVITY OF SUDANESE CARUM CARVI (APIACEAE) FIXED OIL

Prof. Abdel Karim M.*, Tamador A. A. and Khalid M. S.

ABSTRACT

Carum Carvi seed oil was studied by GC-MS. The oil was also assessed for antimicrobial activity. Fourty five components were detected by GC-MS analysis. Main constituents are: 9-octadecenoic acid (z)-methyl ester (45.82%), 9,12-octadecenoic acid(z,z)-methy1 ester(15%), estragole (11.48%). The antibacterial activity of the oil was evaluated via the diffusion assay against five standard pathogenic bacteria (Gram positive: Staphylococcus aureus and Bacillus subtitlis; Gram negative: Esherichia coli and Pseudomonasa aeruginosa and the fungus Candida albicans). With the exception of Bacillus subtilis, Carum carvi oil showed activity against all test organisms at: 50-25mg/ml.The oil exhibited excellent activity against Staphylococcus aureus in the concentration range: 50-25mg/ml. At: 50mg/ml it showed significant activity against the yeast: Candida albicans

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