World Journal of
Pharmaceutical and Life Sciences

A STUDY ON DRUG UTILIZATION AND EVALUATION OF CEPHALOSPORIN’S IN A SECONDARY CARE HOSPITAL

Dr. C.H. Deepthi Reddy* Manvitha Indana, Lavanya, Kranthi Reddy and Likitha

ABSTRACT

Introduction: The aim of the study is to explore possible regional variations and investigate determinants of cephalosporins consumption in a secondary care teaching hospital through DUE studies. The Drug Utilization Evaluation is a recognised quality assurance method used globally which is effective in identifying medicine use problems and as a method in improving pharmaceutical therapy. In this study DUE method was performed to evaluate the utilization pattern of Cephalosporins. Methodology: A prospective observational study on Drug Utilization of cephalosporins was conducted for 150 patients in a secondary care hospital over a 6 months period from August 2017 to January 2017. Results: In this study, we could observe females 97(66.66%) are predominantly prescribed with cephalosporins than males 53(33.33%). Out of 150 prescriptions enrolled, 137 were prescribed with brand name. Most prescribed route of administration for patients was parenteral 134(89.33%). Third generation cephalosporins are most commonly prescribed and Ceftriaxone 108(72%) was widely prescribed. Cephalosporins are generally prescribed for various conditions like pyrexia 68(45.3%), Acute gastritis (12%), Respiratory(4%), Urinary tract infections(9.33%), Uncontrolled Diabetes(2%) and many more. Metronidazole 16(13.18%) was highly co-prescribed antibiotic with cephalosporins. Periodic study on antibiotics enables the health care professionals to select appropriate antibiotic regimen and rationalise its use. Conclusion: The clinical pharmacist has a vital role in achieving rational antibiotic use by minimising their ADR?s. From this, study it was observed that physicians are prescribing cephalosprins more rationally by avoiding banned and newer class of agents.

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