World Journal of
Pharmaceutical and Life Sciences

RENAL AND HAEMATOLOGICAL INDICES OF ACUTE ISCHAEMIC STROKE SUBJECTS IN SOKOTO, NIGERIA

Isa S.A.1 Wali U.* Balarabe S.A. Saidu Y. and Bilbis L.S.

ABSTRACT

Acute ischaemic stroke (AIS) is characterized by elevated level of oxidative stress indices, renal and haematological impairements. Increased oxidative stress is thought to play a pivotal role in the pathophysiology of AIS and its attendant complications. In this study, blood pressure, glucose, urea, creatinine, sodium, potassium, bicarbonate, chloride, red blood cell count, haemoglobin, white blood cell count and platelet counts were determined in 79 AIS patients admitted in Neuro Medical Ward of Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria and the results compared with 20 non acute ischaemic stroke (NAIS) subjects of comparable socio-economic status. The results suggested significant (p<0.05) increase levels of blood pressure, glucose, urea, creatinine, potassium, wbc-count and platelet count and significant (p<0.05) decrease levels of sodium, bicarbonate, chloride, rbc-count and haemoglobin in AIS compared with NAIS subjects. The findings suggest that AIS subjects had impairement of renal and haematological indices as part of associated complications.

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