World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

FORMULATION, DEVELOPMENT AND IN-VITRO EVALUATION OF ORODISPERSIBLE TABLETS OF LAMOTRIGINE

C. Murali Krishna Goud,* K. Kishor Nayak, K. Vijaya and K. Prabandha

ABSTRACT

The aim of the present work is to formulate and develop orodispersible tablets of lamotrigine using different super disintegrating agent by direct compression method. The objective of the study is to increase rapid onset of action of lamotrigine in treatment of epilepsy. The orodispersible tablets of lamotrigine were prepared by diect compression method using different concentration of sodium starch glycolate, crosscarmellose sodium, crospovidone, polyplasdone, indion. The tablet were evaluated for various parameters and results were found to be satisfactory. Total 15 formulations were prepared out of which f13, has shown good results.

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