World Journal of
Pharmaceutical and Life Sciences

ISOLATION AND DETERMINATION OF DNA CONCENTRATION FROM HAIR

Dr. B. Hebsibah Elsie*, P. Sujatha and Mrs. K. Shoba

ABSTRACT

DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA). The information in DNA is stored as a code made up of four chemical bases: adenine (A), guanine (G), cytosine (C), and thymine (T). Human DNA consists of about 3 billion bases, and more than 99 percent of those bases are the same in all people. The order, or sequence, of these bases determines the information available for building and maintaining an organism, similar to the way in which letters of the alphabet appear in a certain order to form words and sentences. To isolate DNA from hair, compare their DNA concentration. The yield of DNA obtained from hair root is highly compared to hair shaft.

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