World Journal of
Pharmaceutical and Life Sciences

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
World Journal of Pharmaceutical and Life Sciences (WJPLS) has indexed with various reputed international bodies like : Google Scholar, Index Copernicus, Indian Science Publications, SOCOLAR, China, Cosmos Impact Factor, Research Bible, Fuchu, Tokyo. JAPAN, Scientific Indexing Services (SIS), Jour Informatics (Under Process), UDLedge Science Citation Index, Global Impact Factor (In Process), International Impact Factor Services, International Scientific Indexing, UAE, International Society for Research Activity (ISRA) Journal Impact Factor (JIF), Science Library Index, Dubai, United Arab Emirates, International Innovative Journal Impact Factor (IIJIF), Scientific Journal Impact Factor (SJIF), Eurasian Scientific Journal Index (ESJI), Indian citation Index (ICI), IFSIJ Measure of Journal Quality, International Scientific Indexing, UAE (ISI), 

Abstract

A SIMPLE UV SPECTROSCOPIC METHOD DEVELOPMENT AND VALIDATION FOR THE QUANTIFICATION OF SIMVASTATIN IN BULK AND ITS FORMULATION

A. Padma*, Dr. K. Thejomoorthy, B. Snehith, Mala Prashanth Kumar, Nandini Tumma

ABSTRACT

A simple, rapid, accurate, precise, selective and economical UV Spectrophotometric method has been developed for estimation of Simvastatin in bulk and its dosage form. Ethanol 30% v/v was used as diluent for the study. The maximum absorption was monitored at 238 nm. The method exhibited linearity in the concentration range of 5- 30?g/ml with correlation coefficient value 0.999. The accuracy of the method was checked at three different levels of 50%, 100% and 150 %. The % recovery was found to be 100.18%. The developed method was validated with respect to accuracy, precision, selectivity, specificity and robustness. All the parameters examined were within the acceptance limits.The above method was a cost-effective quality control tool for routine analysis of Simvastatin in bulk and its pharmaceutical dosage form.

[Full Text Article]

BEST PAPER AWARDS

World Journal of Pharmaceutical and life sciences Will give best paper award in every issue in the from of money along with certificate to promote research .

Best Article of current issue
Dr. Olajide Adedayo Ajayi

Download Article : Click here