World Journal of
Pharmaceutical and Life Sciences

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
World Journal of Pharmaceutical and Life Sciences (WJPLS) has indexed with various reputed international bodies like : Google Scholar, Index Copernicus, Indian Science Publications, SOCOLAR, China, Cosmos Impact Factor, Research Bible, Fuchu, Tokyo. JAPAN, Scientific Indexing Services (SIS), Jour Informatics (Under Process), UDLedge Science Citation Index, Global Impact Factor (In Process), International Impact Factor Services, International Scientific Indexing, UAE, International Society for Research Activity (ISRA) Journal Impact Factor (JIF), Science Library Index, Dubai, United Arab Emirates, International Innovative Journal Impact Factor (IIJIF), Scientific Journal Impact Factor (SJIF), Eurasian Scientific Journal Index (ESJI), Indian citation Index (ICI), IFSIJ Measure of Journal Quality, International Scientific Indexing, UAE (ISI), 

Abstract

PHARMACOLOGICAL STUDY AND EVALUATION OF ANTI-ANXIETY ACTIVITY OF LEAVES OF AZIMA TETRACANTHA

Mrs. Manasi Khadanga*, Durgamadhav Dash, Minesh Ku. Pandey, Supriya Gharami, Damu Sisa1 and Omprakash Shit

ABSTRACT

Pathological anxiety is one of the most common mental disorders in humans. Anxiolytic drugs, mostly belongings to benzodiazepines (BDZ) group & serotonergic groups are widely used to treat anti- anxiety. However the clinical use of these established drugs are associated with a lot of adverse effects.[1] Therefore the development of new drug agent possessing anxiolytic effect with minimal or no adverse effect would be great importance in the treatment of anxiety related disorder. Very high performance is given to the phytoconstituents by the scientific community. for a new anxiolytic agent administered orally for 10 days to Wistar rats for screening effects of anxiolytic effect by using Elevated plus maze (EPM) & Light Dark arnea (LAD)test.[3] The result of our study demonstrated that the ethanolic extract of azima tetracantha leaves has significant anxiolytic activity in EPM & LAD models of anxiety abd supports the traditional use of this plant.[4]

[Full Text Article]

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