World Journal of
Pharmaceutical and Life Sciences

EVALUATION OF ANTHELMINTIC ACTIVITY OF METHANOLIC EXTRACT OF EUPHORBIA NIVULIA

S. Gopi Krishnan*, S. Sanjeevi Raja, J. Vinith Kumar A. S. Joselin and A. Michael Jessika

ABSTRACT

Medicinal plants have been discovered and used in traditional medicinal practice. Medicinal plants produce different chemical compound for its therapeutic potential its widely used now a days as a modern medicine. Various species of Euphorbia nivulia have been extensively studied for their pharmacological activity. The present study was to evaluate the methanolic extract of Euphorbia nivulia against earthworm at four different concentration (5,10,20,30mg/ml). The anthelmintic activity of methanolic extract are compared with standard drug albendazole (10mg/ml). Animal treated with distilled water was taken as a normal control and standard drug solution was prepared in distilled water. Anthelmintic activity was evaluated by noting time required for paralysis and death of worms by extracts. The data shows that methanolic extract (30mg/ml) possess comparable anthelmintic activity with standard drug. The results shows that the present study indicates that medicinal plant has the potential to be used as anthelminitic property.

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