World Journal of
Pharmaceutical and Life Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Life Sciences
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
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Abstract

ULTRASONIC INVESTIGATION OF AQUEOUS DEXTRAN AT DIFFERENT TEMPERATURES AND FREQUENCIES

Subhraraj Panda* and Achyuta Prasad Mahapatra

ABSTRACT

The propagation of Ultrasonic waves in aqueous solution of dextran polymers depends on its viscoelastic behaviour and density which significantly affected with change in temperature and frequency. Therefore the application of low intensity ultrasound, acting as a high frequency dynamic mechanical deformation applied to a polymer, can monitor the changes in acoustic and thermodynamic properties associated with it. In this paper, values of density, viscosity and ultrasonic velocity and related acoustic parameters such as adiabatic compressibility (?), acoustic impedance (Z), relaxation time (?), intermolecular free length (Lf) and Gibb?s free energy (?G), have been determined and the solute-solvent interactions for the aqueous solution of dextran (1%) have been studied at five different temperatures i.e. 30 0C, 35 0C,40 0C,45 0C, 50 0C and four different frequencies i.e. 1MHz, 5MHz, 9MHz, 12MHz. The variation of thermo acoustic parameter with different temperature and frequency leads to the analysis of molecular motion and various types of inter-molecular interaction and their strength of the constituent between solute (dextran) and solvent (distilled water). The results have been interpreted in the light of structural rearrangement occurs in the aqueous dextran solution.

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